Trichodysplasia spinulosa mimicking lichen nitidus in a renal transplant patient

Trichodysplasia spinulosa (TS) is a rare cutaneous condition associated with the TSPyV and characterized by skin‐colored, folliculocentric papules with keratin spicule formation. TS is seen almost exclusively in immunosuppressed individuals, often presenting in patients with a history of solid organ...

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Veröffentlicht in:Pediatric transplantation 2019-06, Vol.23 (4), p.e13394-n/a
Hauptverfasser: Barone, Hope, Brockman, Ross, Johnson, Luke, Al‐Uzri, Amira, Wright, Mary, Mengden‐Koon, Stephanie, Funk, Tracy
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Sprache:eng
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Zusammenfassung:Trichodysplasia spinulosa (TS) is a rare cutaneous condition associated with the TSPyV and characterized by skin‐colored, folliculocentric papules with keratin spicule formation. TS is seen almost exclusively in immunosuppressed individuals, often presenting in patients with a history of solid organ transplantation or chemotherapy for a lymphoreticular malignancy. We report a case of widespread TS in a 9‐year‐old girl with a history of renal transplantation complicated by BK viremia, which is also caused by a polyomavirus, BKPyV. The clinical presentation of TS in this case morphologically resembled the more common, harmless skin condition known as “lichen nitidus,” and was more extensive than expected for TS, creating a diagnostic challenge. This case illustrates an important presentation of severe TS of which transplant teams, oncologists, primary care providers, and dermatologists should be aware.
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.13394