Frontispiece: Visualizing Microglia with a Fluorescence Turn‐On Ugt1a7c Substrate

Fluorescent Probes In their Communication on page 7972 ff., H. S. Je, Y.‐T. Chang, and co‐workers describe the imaging of live microglia using the probe CDr20. Ugt1a7c catalyzes the glucuronidation of CDr20, resulting in red fluorescence.

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Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2019-06, Vol.58 (24), p.n/a
Hauptverfasser:	Kim, Beomsue, Fukuda, Masahiro, Lee, Jung‐Yeol, Su, Dongdong, Sanu, Srikanta, Silvin, Aymeric, Khoo, Audrey T. T., Kwon, Taejoon, Liu, Xiao, Chi, Weijie, Liu, Xiaogang, Choi, Sejong, Wan, Diana S. Y., Park, Sung‐Jin, Kim, Jin‐Soo, Ginhoux, Florent, Je, H. Shawn, Chang, Young‐Tae
Format:	Artikel
Sprache:	eng
Schlagworte:	biological activity Fluorescence Fluorescent indicators fluorescent probes imaging agents Microglia structure–activity relationships Substrates Workers
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Fluorescent Probes In their Communication on page 7972 ff., H. S. Je, Y.‐T. Chang, and co‐workers describe the imaging of live microglia using the probe CDr20. Ugt1a7c catalyzes the glucuronidation of CDr20, resulting in red fluorescence.
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.201982461