Tungstosulfonic acid-catalyzed green synthesis and bioassay of α-aminophosphonates

Tungstosulfonic acid-catalyzed green synthesis and bioassay of α-aminophosphonates

An eco-friendly green synthetic procedure was accomplished through the one-pot three-component synthesis of α -aminophosphonates having –CF 3 moiety in good to excellent yields, under ultrasonication and solvent-free conditions in the presence of tungstosulfonic acid as an efficient, reusable, heter...

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Veröffentlicht in:Monatshefte für Chemie 2019-06, Vol.150 (6), p.1101-1109
Hauptverfasser: Sudileti, Murali, Gundluru, Mohan, Sarva, Santhisudha, Tellamekala, Sreekanth, Hari, Balaji, Meriga, Balaji, Cirandur, Suresh Reddy
Format: Artikel
Sprache:eng
Schlagworte:
Analytical Chemistry
Antiinfectives and antibacterials
Antimicrobial agents
Antioxidants
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Hydrogen peroxide
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
Theoretical and Computational Chemistry
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Zusammenfassung:An eco-friendly green synthetic procedure was accomplished through the one-pot three-component synthesis of α -aminophosphonates having –CF 3 moiety in good to excellent yields, under ultrasonication and solvent-free conditions in the presence of tungstosulfonic acid as an efficient, reusable, heterogeneous solid acid catalyst. All the title compounds were evaluated for their antioxidant activity using DPPH, H 2 O 2 methods and antimicrobial activity by disc diffusion method. The bio-activity revealed that all the title compounds showed significant antioxidant and antimicrobial activities. Graphical abstract
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-019-2385-1