Insulin allergy and immunologic insulin resistance caused by interleukin-6 in a patient with lung cancer

In this case, multiple immune responses to insulin, including immediate allergy, delayed cutaneous hypersensitivity, and immunologie insulin resistance, were thought to have occurred as a paraneoplastic syndrome based on IL-6 secretion by lung cancer because chemotherapy resulted in a decrease of tu...

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Veröffentlicht in:Diabetes care 2006-07, Vol.29 (7), p.1711-1712
Hauptverfasser: Mizuhashi, Satomi, Nakamura, Keigo, Mori, Yasumichi, Noda, Mitsuhiko, Nakanishi, Koji
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container_end_page 1712
container_issue 7
container_start_page 1711
container_title Diabetes care
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creator Mizuhashi, Satomi
Nakamura, Keigo
Mori, Yasumichi
Noda, Mitsuhiko
Nakanishi, Koji
description In this case, multiple immune responses to insulin, including immediate allergy, delayed cutaneous hypersensitivity, and immunologie insulin resistance, were thought to have occurred as a paraneoplastic syndrome based on IL-6 secretion by lung cancer because chemotherapy resulted in a decrease of tumor size, a decline of plasma IL-6, and a reduction of insulin antibodies.
doi_str_mv 10.2337/dc06-0677
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source MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Adenocarcinoma - immunology
Analysis
Chemotherapy
Cytokines
Diabetes
Diabetes Mellitus, Type 2 - complications
Drug Eruptions - immunology
Drug resistance
Humans
Immune system
Insulin
Insulin - immunology
Insulin resistance
Insulin Resistance - immunology
Lung cancer
Lung Neoplasms - immunology
Male
Middle Aged
Paraneoplastic Syndromes - immunology
Plasma
Risk factors
Type 2 diabetes
title Insulin allergy and immunologic insulin resistance caused by interleukin-6 in a patient with lung cancer
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