Insulin allergy and immunologic insulin resistance caused by interleukin-6 in a patient with lung cancer

Insulin allergy and immunologic insulin resistance caused by interleukin-6 in a patient with lung cancer

In this case, multiple immune responses to insulin, including immediate allergy, delayed cutaneous hypersensitivity, and immunologie insulin resistance, were thought to have occurred as a paraneoplastic syndrome based on IL-6 secretion by lung cancer because chemotherapy resulted in a decrease of tu...

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Veröffentlicht in:Diabetes care 2006-07, Vol.29 (7), p.1711-1712
Hauptverfasser: Mizuhashi, Satomi, Nakamura, Keigo, Mori, Yasumichi, Noda, Mitsuhiko, Nakanishi, Koji
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - immunology
Analysis
Chemotherapy
Cytokines
Diabetes
Diabetes Mellitus, Type 2 - complications
Drug Eruptions - immunology
Drug resistance
Humans
Immune system
Insulin
Insulin - immunology
Insulin resistance
Insulin Resistance - immunology
Lung cancer
Lung Neoplasms - immunology
Male
Middle Aged
Paraneoplastic Syndromes - immunology
Plasma
Risk factors
Type 2 diabetes
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Zusammenfassung:In this case, multiple immune responses to insulin, including immediate allergy, delayed cutaneous hypersensitivity, and immunologie insulin resistance, were thought to have occurred as a paraneoplastic syndrome based on IL-6 secretion by lung cancer because chemotherapy resulted in a decrease of tumor size, a decline of plasma IL-6, and a reduction of insulin antibodies.
ISSN:0149-5992
1935-5548
DOI:10.2337/dc06-0677