Antioxidant Activity and Anticancer Effect of Bioactive Peptides from Rainbow Trout (Oncorhynchus mykiss) Skin Hydrolysate

Antioxidant Activity and Anticancer Effect of Bioactive Peptides from Rainbow Trout (Oncorhynchus mykiss) Skin Hydrolysate

In this study, rainbow trout skin ( Oncorhynchus mykiss ) was hydrolyzed using Alcalase (HA) and Flavourzyme (HF) enzymes and bioactive peptides separated by membrane ultrafiltration method ( 30 kDa). The antioxidant properties of the protein hydrolyzed (non-fractionated) and anti-cancer (peptide fr...

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Veröffentlicht in:International journal of peptide research and therapeutics 2020-03, Vol.26 (1), p.625-632
Hauptverfasser: Yaghoubzadeh, Zahra, Peyravii Ghadikolaii, Fatemeh, Kaboosi, Hami, Safari, Reza, Fattahi, Esmail
Format: Artikel
Sprache:eng
Schlagworte:
Animal Anatomy
Antioxidants
Biochemistry
Biomedical and Life Sciences
Cancer
Cytotoxicity
Histology
Life Sciences
Molecular Medicine
Molecular weight
Morphology
Oncorhynchus mykiss
Peptides
Pharmaceutical Sciences/Technology
Pharmacology/Toxicology
Polymer Sciences
Proteins
Salmon
Skin
Subtilisin
Trout
Ultrafiltration
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Zusammenfassung:In this study, rainbow trout skin ( Oncorhynchus mykiss ) was hydrolyzed using Alcalase (HA) and Flavourzyme (HF) enzymes and bioactive peptides separated by membrane ultrafiltration method ( 30 kDa). The antioxidant properties of the protein hydrolyzed (non-fractionated) and anti-cancer (peptide fractions) were evaluated. The results showed that DPPH radical inhibitory power and ferric reducing antioxidant power in hydrolyzed skin protein by Flavourzyme were significantly higher than Alcalase hydrolyzed protein (p 
ISSN:1573-3149
1573-3904
DOI:10.1007/s10989-019-09869-5