Evaluation of the hydroalcoholic extract elaborated with Caesalpinia coriaria Jacq Willd tree fruits in the control of Haemonchus contortus Rudolphi

The aim of this study was to evaluate the in vitro lethal effect of a hydroalcoholic extract (HAE) from C. coriaria fruit against eggs and larvae of H. contortus of domestic ruminants. The HAE was assessed using five concentrations: 50, 25, 12.5, 6.15 and 3.12 mg/mL to eggs and 100, 125, 175, 150 and 200 mg/mL to larvae, respectively; 0.5% ivermectin was used as positive control and 4% methanol in distilled water as negative control. The data of larvicidal and ovicidal effect were analysed with a completely randomised design by ANOVA analysis using the general linear model, while lethal concentrations (LC 50 and LC 90 ) were estimated by a Probit analysis of the SAS programme. A clear HAE-increased concentration dependence effect was observed on eggs and larvae. The highest activity of the HAE was obtained at the highest concentration ( P