Poly (naphthol green B) modified carbon paste electrode for the analysis of paracetamol and norepinephrine

A stable modified carbon paste electrode based on the poly (naphthol green B) film was prepared by electrochemical polymerization method using cyclic voltammetry. The poly (naphthol green B) modified carbon paste electrode showed excellent high electrocatalytic activity towards the paracetamol (PA) and norepinephrine (NE) oxidation, with significant enhancement of the peak currents in neutral pH (7.0) phosphate buffer solution (0.2 M PBS), at the sweep rate 100 mV/s. The sweep rate and pH (6.2 to 7.8) effects on the voltammograms of PA and NE were studied. The lower limit of detection of PA and NE was found to be 1.6 and 2.0 μM, respectively. The simultaneous determination of PA and NE was investigated by cyclic voltammetry (CV). The peak to peak separation of PA and NE was about 173 mV. The interference study was carried out by differential pulse voltammetry (DPV). The modified electrode showed good sensor for the determination of PA and NE. This method was used for the determination of real sample analysis of PA in commercial tablet and NE in injection sample.