A Comprehensive Review on Pronephrium penangianum

A fern, Pronephrium penangianum (Hook.) Holtt., is a highly reputable medicinal plant in tujia ethenomedicine. It has good effect on relaxing muscles and tendons to promoting blood circulation, stanching bleeding and relieving pain in tujia system of medicine. In order to evaluate this traditional plant in a modern perspective, the current review presents essential aspects of Pronephrium penangianum including traditional uses, geographical distribution, chemical constituents, pharmacological studies and standardization. The chemical composition of the herb comprised of flavonoids, phenolic acids, lignans, etc. However, so far there has been few concrete published papers that explicate its chemical therapeutic basis according to Sci‐Finder database and its identification and standardization still remains unknown. This review is intended to summarize the published information of this fern and discuss the current problems for the further studies.