Rhythmic sympathetic nerve discharges in an in vitro neonatal rat brain stem-spinal cord preparation

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 11529, Republic of China To understand the origination of sympathetic nerve discharge (SND), I developed an in vitro brain stem-spinal cord preparation from neonatal rats. Ascorbic acid (3 mM) was added into the bath solution to incre...

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Veröffentlicht in:	Journal of applied physiology (1985) 1999-09, Vol.87 (3), p.1066-1074
1. Verfasser:	Su, Chun-Kuei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn - physiology Ascorbic Acid - pharmacology Biological and medical sciences Brain Brain Stem - drug effects Brain Stem - physiology Carbon Dioxide - metabolism Cardiorespiratory control. Arterial mecano- and chemoreceptor Electrophysiology Fundamental and applied biological sciences. Psychology Nervous system Rats Rats, Sprague-Dawley Respiratory Physiological Phenomena Rodents Spinal cord Spinal Cord - drug effects Spinal Cord - physiology Spinal Nerve Roots - drug effects Spinal Nerve Roots - physiology Splanchnic Nerves - drug effects Splanchnic Nerves - physiology Sympathetic Nervous System - drug effects Sympathetic Nervous System - physiology Temperature Vertebrates: respiratory system
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Zusammenfassung:	Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 11529, Republic of China To understand the origination of sympathetic nerve discharge (SND), I developed an in vitro brain stem-spinal cord preparation from neonatal rats. Ascorbic acid (3 mM) was added into the bath solution to increase the viability of preparations. At 24°C, rhythmic SND (recorded from the splanchnic nerve) was consistently observed, but it became quiescent at
ISSN:	8750-7587 1522-1601
DOI:	10.1152/jappl.1999.87.3.1066