Avermectin B1 5-O-mono-and 4″,5-O, O-bis-derivatization with ethyl succinoyl moiety
Reaction of avermectin B 1 with succinic acid monoethyl ester chloride under catalysis of 2,6-lutidine provided hitherto unknown 5- O -mono- and 4″,5- O, O -bis-derivatives with ethyl succinoyl moiety that are potential antiparasitics.
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| Veröffentlicht in: | Russian chemical bulletin 2019, Vol.68 (3), p.644-647 |
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| container_title | Russian chemical bulletin |
| container_volume | 68 |
| creator | Lyubeshkin, A. V. Shchetinina, M. A. Chernoburova, E. I. Dzhafarov, M. Kh Vasilevich, F. I. Zavarzin, I. V. |
| description | Reaction of avermectin B
1
with succinic acid monoethyl ester chloride under catalysis of 2,6-lutidine provided hitherto unknown 5-
O
-mono- and 4″,5-
O, O
-bis-derivatives with ethyl succinoyl moiety that are potential antiparasitics. |
| doi_str_mv | 10.1007/s11172-019-2469-4 |
| format | Article |
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O
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| ispartof | Russian chemical bulletin, 2019, Vol.68 (3), p.644-647 |
| issn | 1066-5285 1573-9171 |
| language | eng |
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| source | SpringerNature Journals |
| subjects | Brief Communication Catalysis Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry Succinic acid |
| title | Avermectin B1 5-O-mono-and 4″,5-O, O-bis-derivatization with ethyl succinoyl moiety |
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