Avermectin B1 5-O-mono-and 4″,5-O, O-bis-derivatization with ethyl succinoyl moiety

Reaction of avermectin B 1 with succinic acid monoethyl ester chloride under catalysis of 2,6-lutidine provided hitherto unknown 5- O -mono- and 4″,5- O, O -bis-derivatives with ethyl succinoyl moiety that are potential antiparasitics.

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Bibliographische Detailangaben
Veröffentlicht in:	Russian chemical bulletin 2019, Vol.68 (3), p.644-647
Hauptverfasser:	Lyubeshkin, A. V., Shchetinina, M. A., Chernoburova, E. I., Dzhafarov, M. Kh, Vasilevich, F. I., Zavarzin, I. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brief Communication Catalysis Chemistry Chemistry and Materials Science Chemistry/Food Science Inorganic Chemistry Organic Chemistry Succinic acid
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Reaction of avermectin B 1 with succinic acid monoethyl ester chloride under catalysis of 2,6-lutidine provided hitherto unknown 5- O -mono- and 4″,5- O, O -bis-derivatives with ethyl succinoyl moiety that are potential antiparasitics.
ISSN:	1066-5285 1573-9171
DOI:	10.1007/s11172-019-2469-4