A cascade oxidation/[4 + 1] annulation of sulfonium salts for synthesis of polyfunctional furans: DMSO as one carbon source
A novel DMSO-involved cascade reaction of stabilized sulfonium salts has been established for direct construction of polyfunctional furans. This one-pot sequential reaction involving in situ generated α-methylene sulfonium salts was followed by [4 + 1] annulation with sulfur ylides. Notably, DMSO pl...
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Veröffentlicht in: | Organic & biomolecular chemistry 2019-04, Vol.17 (17), p.4311-4316 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A novel DMSO-involved cascade reaction of stabilized sulfonium salts has been established for direct construction of polyfunctional furans. This one-pot sequential reaction involving
in situ
generated α-methylene sulfonium salts was followed by [4 + 1] annulation with sulfur ylides. Notably, DMSO plays a very important role in this transformation, not only as a solvent but also as one carbon source.
A novel DMSO-involved cascade reaction of stabilized sulfonium salts has been established for direct construction of polyfunctional furans. |
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ISSN: | 1477-0520 1477-0539 |
DOI: | 10.1039/c9ob00443b |