ACUTE LYMPHOBLASTIC LEUKÆMIA IN CHILDREN: CLASSIFICATION AND PROGNOSIS

ACUTE LYMPHOBLASTIC LEUKÆMIA IN CHILDREN: CLASSIFICATION AND PROGNOSIS

Immunological (surface-marker) tests have been used to define four subgroups of acute lymphoblastic leukæmia (A.L.L.) in childhood: T-A.L.L., B-A.L.L., common-A.L.L., and null-A.L.L. A study of 94 children shows that the common-A.L.L. subgroup achieves a much longer duration of remission than T-A.L....

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Veröffentlicht in:The Lancet (British edition) 1977-12, Vol.310 (8052), p.1307-1309
Hauptverfasser: Chessells, J.M., Hardisty, R.M., Rapson, N.T., Greaves, M.F.
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Acute lymphoblastic leukemia
Chemotherapy
Children
Children & youth
Disease prevention
Immunology
Leukemia
Lymphocytes T
Medical prognosis
Medical research
Phosphatase
Prognosis
Remission
Subgroups
X-rays
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Zusammenfassung:Immunological (surface-marker) tests have been used to define four subgroups of acute lymphoblastic leukæmia (A.L.L.) in childhood: T-A.L.L., B-A.L.L., common-A.L.L., and null-A.L.L. A study of 94 children shows that the common-A.L.L. subgroup achieves a much longer duration of remission than T-A.L.L.; our findings also confirm the association of some clinical features with T-cell A.L.L. Within the common-A.L.L. subgroup, initial white-cell count correlates with prognosis.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(77)90361-0