TCTAP A-019 Paradoxical Elevation of Cholesterol Efflux Capacity During Acute Coronary Syndrome in Young Heterogenous Asians

[...]assays that quantify apoptotic pathway activation, endothelial vasomotor effects, and antioxidant properties have suggested HDL functional impairment in cardio-metabolic disease states. Most of the young patients in our local data from Sungai Buloh Hospital in Malaysia illustrates that they lack the traditional cardiovascular risk factors such as hypertension, diabetes mellitus and dyslipidemia as opposed to their older counterpart. [...]the young acute coronary syndrome patients in our cohort had low high-density lipoprotein, elevated triglycerides, abnormal carotid-intimal medial thickness and paradoxical elevation of cholesterol efflux capacity.