ABNORMAL LEUCOCYTE COMPOSITION AND SODIUM TRANSPORT IN ESSENTIAL HYPERTENSION

ABNORMAL LEUCOCYTE COMPOSITION AND SODIUM TRANSPORT IN ESSENTIAL HYPERTENSION

Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive pati...

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Veröffentlicht in:The Lancet (British edition) 1975-05, Vol.305 (7914), p.1003-1005
Hauptverfasser: Edmondson, R.P.S., Hilton, P.J., Thomas, R.D., Patrick, J., Jones, N.F.
Format: Artikel
Sprache:eng
Schlagworte:
Abnormalities
Composition
Efflux
Hypertension
Leukocytes
Mental depression
Patients
Sodium
Transport
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Zusammenfassung:Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive patients. These abnormalities in cell sodium transport may possibly be related to mechanisms of hypertension.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(75)91947-9