MgCl2 and its applications in organic chemistry and biochemistry: a review

MgCl 2 has been reported to be a versatile reagent especially as a Lewis acid catalyst in a variety of organic transformations including the preparation of heterocyclic compounds, the protection of functional groups and condensation reaction. Also the use of MgCl 2 in the preparation of metallic magnesium and the application of magnesium chloride in biochemistry such as anesthetic for cephalopods, the separation of serum high-density lipoprotein, effect of MgCl 2 on rabbit bronchial smooth muscle, antimicrobial properties of magnesium chloride and effect of MgCl 2 on the quality of life for patients with fibromyalgia have been reported. Therefore, in this article the use of MgCl 2 in organic chemistry and biochemistry is reviewed. Graphical abstract MgCl 2 has been reported to be a versatile reagent especially as a Lewis acid catalyst in a variety of organic transformations including the preparation of heterocyclic compounds, the protection of functional groups and condensation reaction. Also the use of MgCl 2 in the preparation of metallic magnesium and the application of magnesium chloride in biochemistry such as anesthetic for cephalopods, the separation of serum high-density lipoprotein, effect of MgCl 2 on rabbit bronchial smooth muscle, antimicrobial properties of magnesium chloride and effect of MgCl 2 on the quality of life for patients with fibromyalgia have been reported. Therefore, in this article the use of MgCl 2 in organic chemistry and biochemistry is reviewed.