Modafinil-Associated Clozapine Toxicity

Modafinil-Associated Clozapine Toxicity

Dequardo describes the emergence of clozapine toxicity after modafinil was added to combat sedation associated with treatment. Despite modafinil's potential for reversing clozapine-associated sedation, caution is required when prescribing this drug combination.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The American journal of psychiatry 2002-07, Vol.159 (7), p.1243-a-1244
1. Verfasser: DEQUARDO, JOHN R.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antipsychotic Agents - adverse effects
Antipsychotic Agents - blood
Antipsychotic Agents - pharmacokinetics
Benzhydryl Compounds - adverse effects
Benzhydryl Compounds - pharmacology
Central Nervous System Stimulants - adverse effects
Central Nervous System Stimulants - pharmacology
Clozapine - adverse effects
Clozapine - blood
Clozapine - pharmacokinetics
Dose-Response Relationship, Drug
Drug Interactions
Drug Monitoring
Drug therapy
Humans
Male
Modafinil
Schizophrenia
Schizophrenia - drug therapy
Side effects
Sleep - drug effects
Toxicity
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Dequardo describes the emergence of clozapine toxicity after modafinil was added to combat sedation associated with treatment. Despite modafinil's potential for reversing clozapine-associated sedation, caution is required when prescribing this drug combination.
ISSN:0002-953X
1535-7228
DOI:10.1176/appi.ajp.159.7.1243-a