Diaminodiacid-based synthesis of macrocyclic peptides using 1,2,3-triazole bridges as disulfide bond mimetics

A new approach for the efficient construction of 1,2,3-triazole bridges as disulfide surrogates in peptides, utilizing the diaminodiacid strategy was established. Two thanatin derivatives were prepared with 1,5- and 1,4-disubstituted 1,2,3-triazole diaminodiacids as building blocks. The antibacteria...

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Veröffentlicht in:	RSC advances 2017, Vol.7 (4), p.2110-2114
Hauptverfasser:	Guo, Ye, Liu, Chao, Song, Hui, Wang, Feng-Liang, Zou, Yan, Wu, Qiu-Ye, Hu, Hong-Gang
Format:	Artikel
Sprache:	eng
Schlagworte:	Bridge construction Peptides Triazoles
Online-Zugang:	Volltext
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