Antioxidant Activity of 2,6-Di-tert-butylphenol Derivatives in Lipid Peroxidation and Hydrogen Peroxide Decomposition by Human Erythrocytes in vitro

Antioxidant Activity of 2,6-Di-tert-butylphenol Derivatives in Lipid Peroxidation and Hydrogen Peroxide Decomposition by Human Erythrocytes in vitro

1-(3,5-Di- tert -butyl-4-hydroxyphenyl)propane-1,2-dione dioxime and 3,5-di- tert -butyl-4-hydroxybenzohydrazide showed a high antioxidant efficiency in comparison to the known inhibitors 2,6-di-tertbutylphenol, 2,6-di- tert -butyl-4-mercaptophenol, and 2,6-di-tert-butyl-4-methylphenol (BHT), in mod...

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Veröffentlicht in:Russian journal of general chemistry 2018-12, Vol.88 (12), p.2513-2517
Hauptverfasser: Kolyada, M. N., Osipova, V. P., Berberova, N. T, Shpakovsky, D. B., Milaeva, E. R.
Format: Artikel
Sprache:eng
Schlagworte:
Active oxygen
Analysis
Antioxidants
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Erythrocytes
Hemoglobin
Hydrogen peroxide
Lipid peroxidation
Lipids
Organic acids
Peroxidase
Superoxide
Vitamins
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Zusammenfassung:1-(3,5-Di- tert -butyl-4-hydroxyphenyl)propane-1,2-dione dioxime and 3,5-di- tert -butyl-4-hydroxybenzohydrazide showed a high antioxidant efficiency in comparison to the known inhibitors 2,6-di-tertbutylphenol, 2,6-di- tert -butyl-4-mercaptophenol, and 2,6-di-tert-butyl-4-methylphenol (BHT), in model nonenzymatic human erythrocyte membrane lipid peroxidation.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363218120095