A new route to triphenylpyridines utilizing ketoximes as building blocks via cascade reactions under iron‐organic framework catalysis

Iron‐based metal–organic framework VNU‐20 was utilized as a heterogeneous catalyst for cascade reactions between ketoximes and dibenzyl ether to produce 2,4,6‐triphenylpyridines. Additionally, benzyl alcohol and (dimethoxymethyl)benzene could be used as an alternative starting materials for the transformation. The oxidant exhibited a remarkable impact on the reactions, and di‐tert‐butylperoxide was the most appropriate candidate. The VNU‐20 displayed higher efficiency than many homogeneous and heterogeneous catalysts. The catalyst was reusable for the cascade reactions without a noticeable deterioration in catalytic activity. This transformation is new, and would offer alternative routes to triphenylpyridines utilizing ketoximes as building blocks. VNU‐20 was utilized as a heterogeneouscatalyst for the synthesis of 2,4,6‐triphenylpyridines from ketoximes and dibenzyl ether viacascade reactions.