Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas

Human low-grade gliomas represent a population of brain tumors that remain a therapeutic challenge. Preclinical evaluation of agents, to test their preventive or therapeutic efficacy in these tumors, requires the use of animal models. Spontaneous gliomas develop in models of chemically induced carci...

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Veröffentlicht in:	Journal of neuro-oncology 2001-07, Vol.53 (3), p.243-257
Hauptverfasser:	KISH, Phillip E, BLAIVAS, Mila, STRAWDERMAN, Myla, MURASZKO, Karin M, ROSS, Donald A, ROSS, Brian D, MCMAHON, Gerald
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - therapeutic use Animals Biological and medical sciences Brain Neoplasms - chemically induced Brain Neoplasms - diagnosis Brain Neoplasms - drug therapy Brain Neoplasms - pathology Carcinogens Diet Disease Models, Animal Ethylnitrosourea Glioma - chemically induced Glioma - diagnosis Glioma - drug therapy Glioma - pathology Indoles - therapeutic use Magnetic Resonance Imaging Medical sciences Neoplasms, Multiple Primary Neoplasms, Second Primary - chemically induced Neoplasms, Second Primary - diagnosis Neoplasms, Second Primary - drug therapy Neurology Pyrroles - therapeutic use Rats Rats, Inbred F344 Receptor Protein-Tyrosine Kinases - antagonists & inhibitors Receptors, Growth Factor - antagonists & inhibitors Receptors, Vascular Endothelial Growth Factor Survival Analysis Time Factors Tumors of the nervous system. Phacomatoses Vitamin A - administration & dosage Vitamin A - analogs & derivatives Vitamin A - therapeutic use
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