Biomaterials: Phytochrome‐Based Extracellular Matrix with Reversibly Tunable Mechanical Properties (Adv. Mater. 12/2019)

Biomaterials: Phytochrome‐Based Extracellular Matrix with Reversibly Tunable Mechanical Properties (Adv. Mater. 12/2019)

In article number 1806727, Wilfried Weber and co‐workers present a synthetic extracellular matrix, the mechanical properties of which can be tuned in a fast and reversible manner by light in the red spectrum. They apply this matrix to optically control the migration of primary T lymphocytes and to a...

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Veröffentlicht in:Advanced materials (Weinheim) 2019-03, Vol.31 (12), p.n/a
Hauptverfasser: Hörner, Maximilian, Raute, Katrin, Hummel, Barbara, Madl, Josef, Creusen, Guido, Thomas, Oliver S., Christen, Erik H., Hotz, Natascha, Gübeli, Raphael J., Engesser, Raphael, Rebmann, Balder, Lauer, Jasmin, Rolauffs, Bernd, Timmer, Jens, Schamel, Wolfgang W. A., Pruszak, Jan, Römer, Winfried, Zurbriggen, Matias D., Friedrich, Christian, Walther, Andreas, Minguet, Susana, Sawarkar, Ritwick, Weber, Wilfried
Format: Artikel
Sprache:eng
Schlagworte:
biomaterials
Biomedical materials
cell migration
Extracellular matrix
Lymphocytes
Mechanical properties
mechanosignaling
Migration
optogenetics
phytochromes
Stem cells
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Zusammenfassung:In article number 1806727, Wilfried Weber and co‐workers present a synthetic extracellular matrix, the mechanical properties of which can be tuned in a fast and reversible manner by light in the red spectrum. They apply this matrix to optically control the migration of primary T lymphocytes and to analyze mechanosignalling in mesenchymal stem cells in response to dynamic mechanical cues. Cover image designed by Jo Richers (www.jorichers.com).
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201970083