Evaluation of In Vitro Antiurolithiatic Activity of Vigna radiata

Furthermore, although some drugs used to prevent the disease have some positive effects, they are not effective in all patients and often have adverse effects that compromise their use in long-term medical treatment.4 Kidney stone disease is a multi-factorial disorder resulting from the combined influence of epidemiological, biochemical and genetic risk factors3. The aerial parts of Herniariahirsuta, widely distributed in the Mediterranean area, is used in folk medicine as a diuretic and to treat kidney stones6Though technological advancements have made dramatic improvement in the removal of urinary stones still some of the drawbacks of these methods exists which includes their being too costly for a common man and recurrence of stone formation along with a number of other side effects.7 Management of stone disease depends on the size and location of the stones. The experimental kidney stones of calcium oxalate (CaOx) were prepared in the laboratory by taking equimolar solution of calcium chloride dehydrate in distilled water and sodium oxalate in 10 ml of 2N H2SO4. First group served as blank containing only1 mg of calcium oxalate.