Formulation, Characterization and Applications on Solid Lipid Nanoparticles-A Review

The drug contained solid lipid is milled by means of ball mill or mortar. [...]particle size measure with in the range was about 50 -100 microns. [...]SLN can be prepared by the rapid expansion of supercritical carbon dioxide solution RESS method. it should be in mild pressure. 6)MICROEMULSION BASED METHOD: Tablets and Pellets.) For facilitate fast lipid crystallization and to avoid aggregation, more water required for the low particle content in SLN dispersion. Because of dilution step; attainable lipid contents are considerably lower compared with the HPH based formulations. 7)SPRAY DRYING METHOD: [...]the aqueous solution which incorporates the emulsions was added, Using the ultrasound with the probe to diffuser eventually, the SLN with the microscopic and uniform particle size is added. [...]lipid + tranquilizer include to natural arrangements. 11) SOLVENT INJECTION TECHNIQUE: