Estimation of Alkaline Phosphatase level in the Serum and Saliva of Hypothyroid Patients with and without Periodontitis

[...]this study was established to measure the level of ALP in serum and saliva of hypothyroid patients with and without periodontitis. The diagnosis was made through specialized dentists in the department of Periodontics, College of Dentistry- Baghdad University. Besides 30 (3 males and 27 females) volunteers subjects, considered as control, their ages and gender were matched with patients; their ages ranged between (2055) years. [...]pituitary gland responds to that failure by secreting more TSH, raising serum TSH levels fairly before there is a detectable decline in circulating thyroid hormones T4 and T3, afterward, the levels of ÍT4 and ÍT3 reduced (17). [...]the present study provides evidence that activity of ALP is dropped significantly in serum indicate that bone resorption occurs at a lower rate as a result of decline thyroid hormones, which can affect oral health, concluded alveolar bone and periodontal tissue destruction indirectly Received on 04.10.2017 Modified on 26.11.2017 Accepted on 21.12.2017 © RJPT All right reserved Research J. Pharm. and Tech 2018; 11(7): 2993-2996.