High genetic diversity of noroviruses in children from a community-based study in Rio de Janeiro, Brazil, 2014-2018

We report on the occurrence and diversity of noroviruses in children (younger than 5 years old of age) from a low-income urban area in Rio de Janeiro, Brazil. Sixty-one stool specimens collected from children between 1 and 4 years old with acute diarrhoeic episodes (ADE) and non-ADE were investigate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of virology 2019-05, Vol.164 (5), p.1427-1432
Hauptverfasser:	Cantelli, Carina Pacheco, da Silva, Marcelle Figueira Marques, Fumian, Tulio Machado, da Cunha, Denise Cotrim, Andrade, Juliana da Silva Ribeiro de, Malta, Fábio Correia, da Silva e Mouta Junior, Sérgio, Fialho, Alexandre Madi, de Moraes, Marcia Terezinha Baroni, Brasil, Patricia, Miagostovich, Marize Pereira, Leite, José Paulo Gagliardi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Brief Report Children Genetic diversity Genotypes Infectious Diseases Medical Microbiology Polymerase chain reaction Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We report on the occurrence and diversity of noroviruses in children (younger than 5 years old of age) from a low-income urban area in Rio de Janeiro, Brazil. Sixty-one stool specimens collected from children between 1 and 4 years old with acute diarrhoeic episodes (ADE) and non-ADE were investigated. RT-qPCR and sequencing of PCR products after conventional RT-PCR analysis were performed. Noroviruses were detected in 29 (47.5%) samples: 21 (46.7%) from cases with ADE and 8 (50%) from non-ADE cases. Molecular characterization showed 10 different genotypes circulating in this community between November 2014 and April 2018.
ISSN:	0304-8608 1432-8798
DOI:	10.1007/s00705-019-04195-z