BReDi mouse: A novel transgenic mouse strain to track and deplete B cells
BReDi mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in B cells. B cells can be effectively visualized by red fluorescence and can be efficiently depleted in a highly controlled fashion to study their functional capacity in vivo.
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Veröffentlicht in: | European journal of immunology 2019-03, Vol.49 (3), p.500-503 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | BReDi mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in B cells. B cells can be effectively visualized by red fluorescence and can be efficiently depleted in a highly controlled fashion to study their functional capacity in vivo. |
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ISSN: | 0014-2980 1521-4141 |
DOI: | 10.1002/eji.201847930 |