BReDi mouse: A novel transgenic mouse strain to track and deplete B cells

BReDi mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in B cells. B cells can be effectively visualized by red fluorescence and can be efficiently depleted in a highly controlled fashion to study their functional capacity in vivo.

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Veröffentlicht in:European journal of immunology 2019-03, Vol.49 (3), p.500-503
Hauptverfasser: Mues, Marsilius, Krishnamoorthy, Gurumoorthy
Format: Artikel
Sprache:eng
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Zusammenfassung:BReDi mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in B cells. B cells can be effectively visualized by red fluorescence and can be efficiently depleted in a highly controlled fashion to study their functional capacity in vivo.
ISSN:0014-2980
1521-4141
DOI:10.1002/eji.201847930