Toxic effects of magnetic nanoparticles on normal cells and organs

Magnetic nanoparticles (MNPs) are promising candidates for drug delivery and treatment of various disorders. Toxicity evaluation is a critical point in the development of nanoformulations and therefore, draws considerable attention. Formulations involving individual or combinatorial nanoparticle sus...

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Veröffentlicht in:Life sciences (1973) 2019-03, Vol.220, p.156-161
Hauptverfasser: Jiang, Ziyu, Shan, Kuizhong, Song, Jie, Liu, Jingbing, Rajendran, Suresh, Pugazhendhi, Arivalagan, Jacob, Joe Antony, Chen, Baoan
Format: Artikel
Sprache:eng
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Zusammenfassung:Magnetic nanoparticles (MNPs) are promising candidates for drug delivery and treatment of various disorders. Toxicity evaluation is a critical point in the development of nanoformulations and therefore, draws considerable attention. Formulations involving individual or combinatorial nanoparticle suspensions might be used for targeted delivery and treatment. This might be a evaluated further for safety related issues considering future medications based on MNPs. Nanoparticle distribution in the body is dependent on its surface characteristics. Size, dose and routes of nanoparticle entry have to be taken into consideration for future assays. [Display omitted]
ISSN:0024-3205
1879-0631
DOI:10.1016/j.lfs.2019.01.056