Nootropic activity of ethanolic extract of Alangium salvifolium leaves on Scopolamine mouse model of Alzheimer's disease

[...]various antioxidant therapy and flavonoids elements may also be useful for protecting brain functions and bar the age-related deficits. [...]scopolamine-induced memory impairment could be an effective model for the assessment of anti-amnesic properties of the most recent pharmaceutical medicati...

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Veröffentlicht in:National journal of physiology, pharmacy and pharmacology pharmacy and pharmacology, 2018, Vol.8 (9), p.1-1630
Hauptverfasser: K, Parameshwari, Kumar, Shashi, G, Priyadharshini, C, Prathima, C, Neetha
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Sprache:eng
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Zusammenfassung:[...]various antioxidant therapy and flavonoids elements may also be useful for protecting brain functions and bar the age-related deficits. [...]scopolamine-induced memory impairment could be an effective model for the assessment of anti-amnesic properties of the most recent pharmaceutical medication. Numerous activity animal models are generally used for the assessment and substantiation of recent medication in contradiction of dementia[2] In the present study, 7 days pre-treatment of animals with A. Salvifolium leaves extract considerably counteracted the reduction of the percentage of spontaneous alternation triggered through scopolamine suggesting significant improvement of area-related short-term memory by the EASL. [23] Some parameters of the EPM at the side of retention TL (the time taken by suggests that of the animal to move from the open palms to the penned arms) are employed for the analysis of memory. [...]an animal that has formerly (acquisition trial) delicate entering the open hands have the shortened switch latency among the retention trial.
ISSN:2320-4672
2231-3206
DOI:10.5455/njppp.2018.8.0928322092018