Effect of Ehretia microphylla on the blood cholesterol and weight of ICR mice (Mus musculus)

Received: February 20, 2018; Accepted: March 04, 2018 ABSTRACT Background: Simvastatin has been widely used in controlling blood cholesterol levels and weight; however, side effects such as muscle pain, muscle damage, liver damage, and hyperglycemia may occur. Afterward, analysis after administration of the different treatments showed that significant differences are seen at day 42. [...]all the treatment groups are not different with each other except the positive control and high dose and the low and mid dose. [25] Furthermore, assessment of the different groups shows that the high dose of E. microphylla may have the same effect as simvastatin. Since E. microphylla is a natural supplement, toxic effects may be lesser and may not be observed at all. [...]since E. microphylla is a natural remedy, it may have lesser side effects when compared with the use of simvastatin on prolonged administration.