Improvement of signal reproducibility and matrix/comatrix effects in MALDI analysis
A study examined the main problems associated with matrix-assisted laser desorption/ionization quantitative analysis: poor shot-to-shot reproducibility, crystal inhomogeneity, signal degradation and data acquisition system nonlinearity.
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Veröffentlicht in: | Analytical chemistry (Washington) 1995-03, Vol.67 (6), p.1034-1041 |
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container_title | Analytical chemistry (Washington) |
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creator | Gusev, Arkady I. Wilkinson, William R. Proctor, Andrew Hercules, David M. |
description | A study examined the main problems associated with matrix-assisted laser desorption/ionization quantitative analysis: poor shot-to-shot reproducibility, crystal inhomogeneity, signal degradation and data acquisition system nonlinearity. |
doi_str_mv | 10.1021/ac00102a003 |
format | Article |
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issn | 0003-2700 1520-6882 |
language | eng |
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source | ACS Publications |
subjects | Chemistry Ions Lasers Scientific imaging |
title | Improvement of signal reproducibility and matrix/comatrix effects in MALDI analysis |
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