Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nulceation by Arp2/3 complex and bacterial actin-based motility

Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nulceation by Arp2/3 complex and bacterial actin-based motility

To propel itself in infected cells, the pathogen Shigella flexneri subverts the Cdc42-controlled machinery responsible for actin assembly during filopodia formation.

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Bibliographische Detailangaben
Veröffentlicht in:The Journal of cell biology 1999-09, Vol.146 (6), p.1319
Hauptverfasser: Egile, Coumaran, Loisel, Thomas P, Laurent, Valerie, Li, Rong
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria
Cells
Cellular biology
Online-Zugang:Volltext
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Zusammenfassung:To propel itself in infected cells, the pathogen Shigella flexneri subverts the Cdc42-controlled machinery responsible for actin assembly during filopodia formation.
ISSN:0021-9525
1540-8140