Adverse reactions associated with the use of eugenol in dentistry

Key Points Eugenol has a long history of successful therapeutic use in dentistry, but has the capacity to cause adverse effects Eugenol is cytotoxic at high concentrations and can cause allergic reactions in sensitised patients This paper illustrates cases of such reactions occurring in general dental practice Eugenol is a material commonly used in dentistry with few reported side effects. It is not however, a bio-friendly material when in contact with oral soft tissues. It can produce both local irritative and cytotoxic effects, as well as hypersensitivity reactions. Here we report on two cases of adverse local reaction to eugenol, contained within a temporary restorative material and a temporary cementation material respectively, which illustrate these problems.