INFLUENCE OF CHLORANTRANILIPROLE TOXICITY ON IONIC REGULATION OF GILL AND MUSCLE ATPASE ACTIVITY OF NILE FISH {OREOCHROMISNILOTICUS

The objective of this study is to determine the effects of chlorantraniliprole (CHL) pesticide on ATPases (Na+/K+ ATPase. Ca2+ ATPase and Mg2+ ATPase) of gill and muscle in O. niloticus. Fish were exposed to acute and chronic chlorantraniliprole (CHL) exposure (0.5. 1.5 and 3.0 nig/L). UV-vis spectrophotometry methods were used to determining enzymes activity. When compared to control fish, the most inhibitions determined to Ca2+ ATPase > Na+/K+ ATPase > Mg2+ ATPase on gill and muscle tissues. This work showed that Ca2+ ATPase is more sensitive biomarker chlorantramliprole (CHL) pesticide than other ATPase enzvmes. In our studv. O. nifattens could be a suitable biomarker for chlorantra-niliprole (CHL) and ATPases are very important early warning ecotoxicologic.