Synthesis of 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one - a semi-product of the synthesis of antiviral drug triazide® in the conditions of microwave excitation

Synthesis of 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one - a semi-product of the synthesis of antiviral drug triazide® in the conditions of microwave excitation

5-Methyl-1,2,4-triazolo[1,5-a]pyrimidine-7(4H)-one was synthesized (the intermediate product for the syn-thesis of the antiviral drug Triazide®) under microwave radiation. Conversion of the starting reagents to the target product reached 95% due to experimentally selected conditions.

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Bibliographische Detailangaben
Hauptverfasser: Baklykov, Artem V., Rusinov, Gennady L., Artem’ev, Grigory A., Kopchuk, Dmitry S., Zyryanov, Grigory V., Rusinov, Vladimir L., Charushin, Valery N.
Format: Tagungsbericht
Sprache:eng
Schlagworte:
Microwaves
Reagents
Synthesis
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Beschreibung
Zusammenfassung:5-Methyl-1,2,4-triazolo[1,5-a]pyrimidine-7(4H)-one was synthesized (the intermediate product for the syn-thesis of the antiviral drug Triazide®) under microwave radiation. Conversion of the starting reagents to the target product reached 95% due to experimentally selected conditions.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.5087337