Visible‐Light‐Mediated α‐Oxygenation of 3‐(N,N‐Dimethylaminomethyl)‐Indoles to Aldehydes

The visible‐light‐mediated oxygenation of 3‐N,N‐(dimethylaminomethyl)‐indoles bearing various substituents afforded a series of 3‐carbaindole derivatives. Herein we describe the reaction scope, a plausible mechanism and a practical application of this transformation in the formal synthesis of (–)‐vincorine is described as well. 3‐Carbaindole derivatives can be accessed through a visible‐light‐mediated oxygenation of 3‐N,N‐(dimethylaminomethyl)‐indoles bearing various substituents. A plausible mechanism and practical application of this transformation in formal synthesis of (–)‐Vincorine is also described.