Sodium dodecyl sulfate-resistant complexes of Alzheimer's amyloid (beta)-peptide with the N-terminal, receptor binding domain of apolipoprotein E

Sodium dodecyl sulfate-resistant complexes of Alzheimer's amyloid (beta)-peptide with the N-terminal, receptor binding domain of apolipoprotein E

Immunocytochemical, biochemical, and molecular genetic studies indicate that apolipoprotein E (apoE) plays an important role in the process of amyloidogenesis-beta. However, there is still no clear translation of these data into the pathogenesis of amyloidosis-beta.

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Bibliographische Detailangaben
Veröffentlicht in:Biophysical journal 2000-08, Vol.79 (2), p.1008
Hauptverfasser: Golabek, Adam A, Kida, Elizabeth, Walus, Mariusz, Perez, Christian
Format: Artikel
Sprache:eng
Schlagworte:
Alzheimer's disease
Biochemistry
Neurology
Peptides
Proteins
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Beschreibung
Zusammenfassung:Immunocytochemical, biochemical, and molecular genetic studies indicate that apolipoprotein E (apoE) plays an important role in the process of amyloidogenesis-beta. However, there is still no clear translation of these data into the pathogenesis of amyloidosis-beta.
ISSN:0006-3495
1542-0086