Pathogenesis of rheumatoid arthritis

Rheumatoid arthritis is thought of as a prototypical autoimmune disease, but its aetiology is not known. The role of collagenous or mycobacterial stimuli in animals is studied for parallels with human disease.

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Bibliographische Detailangaben
Veröffentlicht in:	The Lancet (British edition) 1993-01, Vol.341 (8840), p.283-286
Hauptverfasser:	Sewell, K.L., Trentham, D.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antigens Arthritis Arthritis, Rheumatoid - etiology Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - immunology Autoantibodies - immunology Autoimmune diseases Binding sites Biological and medical sciences Cartilage Collagen Cytokines Cytokines - immunology Disease Models, Animal Diseases of the osteoarticular system Humans Immunity (Disease) Immunoglobulins Inflammatory joint diseases Joints - immunology Laboratory animals Lymphocytes Medical research Medical sciences Pathogenesis Patients Peptides Receptors, Antigen, T-Cell - immunology Rheumatism Rheumatoid arthritis T-Lymphocytes - immunology Tumor necrosis factor-TNF
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Beschreibung
Zusammenfassung:	Rheumatoid arthritis is thought of as a prototypical autoimmune disease, but its aetiology is not known. The role of collagenous or mycobacterial stimuli in animals is studied for parallels with human disease.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/0140-6736(93)92627-6