ENDEMIC GOITRE IN CENTRAL CHINA CAUSED BY EXCESSIVE IODINE INTAKE

ENDEMIC GOITRE IN CENTRAL CHINA CAUSED BY EXCESSIVE IODINE INTAKE

Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 μg/1. Goitres were present in 65% (n = 120) and 15.4% (n=51), respectively. All children in both groups were clinically euthyroid and neurologically normal....

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Veröffentlicht in:The Lancet (British edition) 1987-08, Vol.330 (8553), p.257-259
Hauptverfasser: Mu, Li, Chengyi, Qu, Qidong, Qian, Qingzhen, Jia, Eastman, CreswellJ, Collins, JohnK, Derun, Liu, Peiying, Zhang, Chunde, Zhang, Huaixing, Wang, Boyages, StevenC, Jupp, JamesJ, Maberly, GlenF
Format: Artikel
Sprache:eng
Schlagworte:
Children
Drinking water
Hypothyroidism
Iodine
Thyroid
Thyroid gland
Thyroid hormones
Thyroid-stimulating hormone
Thyroxine
Triiodothyronine
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Zusammenfassung:Thyroid status was examined in children from two villages in central China where the iodine concentrations in drinking water were 462.5 and 54 μg/1. Goitres were present in 65% (n = 120) and 15.4% (n=51), respectively. All children in both groups were clinically euthyroid and neurologically normal. Growth measurements and intellectual performance were similar in the two groups. Children from the high-iodine village had a lower mean serum triiodothyronine and higher serum free thyroxine and serum thyroid-stimulating hormone concentrations than the children from the control village. 2 cases of overt hypothyroidism were detected in the high-iodine village.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(87)90838-5