Effects of hypertension, diabetes and the joint action of the two on the new chronic kidney disease

Objective To investigate the effects of hypertension, diabetes and the joint action of the two on the new chronic kidney disease (CKD). Methods This is a prospective cohort study. A total of 101,510 on job and retired Kailuan employees who participated in 2006-2007 annual physical examinations were as the research objects. Those without baseline data, and patients with CKD, cancer and history of cardiovascular and cerebrovascular diseases were excluded, and those with no physical examination during follow-up or missing follow-up data were also excluded, then 51,156 cases were included in the final analysis and divided into 4 groups: normal blood pressure (BP) and fasting blood glucose (FBG) group, hypertension group, diabetes group and hypertension+diabetes group. Multivariate COX risk proportional regression was performed to analyze the effect of hypertension, diabetes and the joint action of the two on the new CKD. Results After an average of 7.3±2.3 years follow-up, 8,179 participants were found to have