Drug hypersensitivity syndrome to carbamazepine and human herpes virus 6 infection: Case report and literature review

We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6). The potential role of HHV-6 regarding the drug-induced hypersensitivity syndrome is discussed and the main clinical features of this potentially...

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Veröffentlicht in:	Infection 2003-08, Vol.31 (4), p.254-256
Hauptverfasser:	ZELLER, A, SCHAUB, N, STEFFEN, I, BATTEGAY, E, HIRSCH, H. H, BIRCHER, A. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Base Sequence Biological and medical sciences Carbamazepine - adverse effects Carbamazepine - therapeutic use Drug Hypersensitivity - complications Drug Hypersensitivity - diagnosis Drug toxicity and drugs side effects treatment Female Follow-Up Studies Herpesvirus 6, Human - isolation & purification Humans Hypersensitivity Literature reviews Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Molecular Sequence Data Pharmacology. Drug treatments Polymerase Chain Reaction Risk Assessment Roseolovirus Infections - complications Roseolovirus Infections - diagnosis Seizures - diagnosis Seizures - drug therapy
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Zusammenfassung:	We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6). The potential role of HHV-6 regarding the drug-induced hypersensitivity syndrome is discussed and the main clinical features of this potentially fatal adverse drug reaction are highlighted.
ISSN:	0300-8126 1439-0973
DOI:	10.1007/s15010-002-3099-5