PHENYTOIN TERATOGENICITY IN MAN

PHENYTOIN TERATOGENICITY IN MAN

7 infants who all demonstrated similar skeletal abnormalities and were born to mothers taking phenytoin throughout pregnancy are reported. One of these mothers had severe phenytoin toxicity in the early months of pregnancy. Serum-phenytoin levels in women of childbearing age must be controlled until...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Lancet (British edition) 1973-01, Vol.301 (7794), p.70-72
Hauptverfasser: Loughnan, PeterM, Vance, JohnC, Gold, Hugo
Format: Artikel
Sprache:eng
Schlagworte:
Abnormalities
Anticonvulsants
Babies
Chromosomes
Fingers & toes
Hernias
Infants
Metabolism
Phenytoin
Pregnancy
Teratogenicity
Toxicity
Twins
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:7 infants who all demonstrated similar skeletal abnormalities and were born to mothers taking phenytoin throughout pregnancy are reported. One of these mothers had severe phenytoin toxicity in the early months of pregnancy. Serum-phenytoin levels in women of childbearing age must be controlled until the ætiological role of phenytoin in human malformation is further evaluated.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(73)90467-4