RELATIVE EFFICACY OF BLOOD, URINE, RECTAL SWAB, BONE-MARROW, AND ROSE-SPOT CULTURES FOR RECOVERY OF SALMONELLA TYPHI IN TYPHOID FEVER

RELATIVE EFFICACY OF BLOOD, URINE, RECTAL SWAB, BONE-MARROW, AND ROSE-SPOT CULTURES FOR RECOVERY OF SALMONELLA TYPHI IN TYPHOID FEVER

The recovery of Salmonella typhi from blood, rectal swab, urine, bone-marrow, and rose spots was compared in 62 patients with typhoid fever, most of whom had received some antibiotic therapy before presentation. S. typhi was isolated from culture of bone-marrow in 56 patients (90%); in contrast, S....

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Veröffentlicht in:The Lancet (British edition) 1975-05, Vol.305 (7918), p.1211-1213
Hauptverfasser: Gilman, RobertH, Terminel, Miguel, Levine, MyronM, Hernandez-Mendoza, Pablo, Hornick, RichardB
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Blood
Bone marrow
Fever
Patients
Recovery
Recovery (Medical)
Rectum
Salmonella
Typhoid
Urine
Vaccines
Waterborne diseases
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Zusammenfassung:The recovery of Salmonella typhi from blood, rectal swab, urine, bone-marrow, and rose spots was compared in 62 patients with typhoid fever, most of whom had received some antibiotic therapy before presentation. S. typhi was isolated from culture of bone-marrow in 56 patients (90%); in contrast, S. typhi was recovered from blood in only 25 (40%), from stool in 23 (37%), and urine in 4 (7%). S. typhi was isolated from 24 (63%) of 38 patients who had rose-spot cultures. If culture sites had been limited to blood, stool, and urine, the bacteriological diagnosis would have been missed in 24 patients.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(75)92194-7