Influence of Baicalin and Octreotide on NF-[kappa]B and P-Selectin Expression in Liver and Kidney of Rats with Severe Acute Pancreatitis

To observe the influence of Baicalin and Octreotide on liver and kidney of rats with severe acute pancreatitis (SAP) and discuss the related mechanism. SAP rats were randomly divided into model control, Baicalin treated and Octreotide treated group (n=45). The same number of normal rats were included in sham-operated group (n=45). In all groups, the mortality rate, pathological changes as well as expression levels of NF-κB p65 and P-selectin protein in liver and kidney were observed at 3, 6 and 12 h after operation. The survival rate of treated group was 100% at 12 h significantly higher than that of model control group (P