Two-dimensional biomechanical thumb model for pipetting

Manual pipetting imposes repetitive movements, high force, and awkward postures on the thumb, fingers, and wrist, increasing the risk of musculoskeletal injuries. The purpose of this study is to provide a linear regression model to estimate the optimal pipetting grip height based on the two-dimensional biomechanical static thumb model developed in this study. This biomechanical static thumb model uses hand anatomy and static equilibrium conditions to estimate internal tendon forces against a given external force. Based on the model, we conclude that the optimal grip height is 3 cm in males and 2 cm in females in terms of grip strength and force efficiency. In addition, the model is validated by RMS EMG data from correlation analysis between the predicted internal tendon forces, with RMS EMG values of 0.65 for Flexor Pollicis Longus, 0.57 for Flexor Pollicis Brevis, and 0.61 for Adductor Pollicis. •Internal tendon forces of FPL, FPB, and ADD were predicted by the biomechanical thumb model.•Optimal grip height of pipetting was suggested based on the grip strength and force efficiency.•The biomechanical thumb model was validated by RMS EMG values.•The regression model can be used for finding optimal grip height simply and quickly in the workstation.