A case of non-Hodgkin’s lymphoma of the ovary: Usefulness of18F-FDG PET for staging and assessment of the therapeutic response

Primary ovarian lymphoma as the initial manifestation is rare. A 27-year-old woman presented to our hospital with the symptoms of lower abdominal fullness and pollakisuria. CT scan and MRI revealed bilateral ovarian tumors, which showed heterogeneous masses.^sup 18^F-FDG PET revealed strong uptake by the abdominal masses, and the maximum standardized uptake value (SUV^sub max^) was 12.5. Abnormal uptake was not shown by other regions. An exploratory laparotomy was performed. Histological findings revealed diffuse large B-cell lymphoma. The clinical stage was IV according to the Ann Arbor system. International prognostic index (IPI) was 3 (high-intermediate risk). Chemotherapy was administered consisting of three courses of an R-CHOP regimen, and^sup 18^F-FDG PET and CT scan revealed no signs of involvement 3 months after initiation of the chemotherapy.^sup 18^F-FDG PET was a useful method for staging and assessment of the therapeutic response in primary ovarian lymphoma.[PUBLICATION ABSTRACT]