IMMUNE COMPLEXES IN OVARIAN CANCER

IMMUNE COMPLEXES IN OVARIAN CANCER

Immune complexes have been assayed in ovarian cancer with a polyethylene-glycol (P.E.G.) precipitation assay and a Clq solid-phase assay. Significantly higher levels of immune complexes were detected in patients in relapse compared with those in remission. Remission values were within the range obta...

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Veröffentlicht in:The Lancet (British edition) 1978-07, Vol.312 (8080), p.72-73
Hauptverfasser: Poulton, T.A., Crowther, M.E., Hay, F.C., Nineham, L.J.
Format: Artikel
Sprache:eng
Schlagworte:
Antigen-antibody complexes
Assaying
Cancer
Chemical precipitation
Ovarian cancer
Polyethylene glycol
Polyethylenes
Remission
Solid phases
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Zusammenfassung:Immune complexes have been assayed in ovarian cancer with a polyethylene-glycol (P.E.G.) precipitation assay and a Clq solid-phase assay. Significantly higher levels of immune complexes were detected in patients in relapse compared with those in remission. Remission values were within the range obtained for a control group. Evidence was produced that immune-complex levels rise before the clinical detection of relapse, and it is suggested that the P.E.G. assay could be a useful marker of disease progress.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(78)91383-1