HUMAN EMBRYONIC PREALBUMIN AS A MARKER FOR TUMOURS AND FIBROBLASTS

HUMAN EMBRYONIC PREALBUMIN AS A MARKER FOR TUMOURS AND FIBROBLASTS

Embryonic prealbumin (E.P.A.) was demonstrated by agar immunodiffusion in 122 out of 505 homogenates of various tumours and in 7 out of 20 serum samples from patients with connective-tissue tumours. Analogous antigen was found in human embryonic and adult cultured fibroblasts. This newly identified...

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Veröffentlicht in:The Lancet (British edition) 1978-11, Vol.312 (8100), p.1122-1123
Hauptverfasser: Tatarinov, YuS, Vasiliev, M.Yu, Kalashnikov, V.V., Voloshuk, S.G., Kraevsky, N.A., Vorsanova, S.G.
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Embryo fibroblasts
Embryos
Fibroblasts
Immunodiffusion
Patients
Tumors
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Zusammenfassung:Embryonic prealbumin (E.P.A.) was demonstrated by agar immunodiffusion in 122 out of 505 homogenates of various tumours and in 7 out of 20 serum samples from patients with connective-tissue tumours. Analogous antigen was found in human embryonic and adult cultured fibroblasts. This newly identified antigen is probably actively secreted by fibroblasts into the circulation of patients with tumours.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(78)92276-6