The synthesis and metabolism of asymmetric dimethylarginine (ADMA)

The synthesis and metabolism of asymmetric dimethylarginine (ADMA)

Numerous reports have indicated that the plasma concentration of endogenously produced inhibitors of nitric oxide synthase are elevated in human disease states. In this review we discuss recent advances in our understanding of the enzymes responsible for the synthesis and metabolism of these inhibit...

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Veröffentlicht in:European journal of clinical pharmacology 2006-02, Vol.62 (S1), p.33-38
Hauptverfasser: Leiper, James M., Vallance, Patrick
Format: Artikel
Sprache:eng
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Zusammenfassung:Numerous reports have indicated that the plasma concentration of endogenously produced inhibitors of nitric oxide synthase are elevated in human disease states. In this review we discuss recent advances in our understanding of the enzymes responsible for the synthesis and metabolism of these inhibitors.
ISSN:0031-6970
1432-1041
DOI:10.1007/s00228-005-0013-y